Mississippi State (21-11) will move on to face seventh-seeded Missouri (21-10) in the second round on Thursday night.
The Bulldogs shot 52% (35 of 67) overall, including 15 of 34 (44%) from long range. Hubbard finished 9 of 19 from the floor, while nine other Bulldogs scored at least five points.
LSU had 22 made field goals (39%) and 15 turnovers to end the season on a six-game skid.
Jordan Sears made three 3-pointers and scored 20 points to lead LSU (14-18). Robert Miller III added 14 points and Cam Carter had 13.
Hubbard scored 16 points in the first half to help Mississippi State build a 44-24 lead at the break. LSU pulled to 51-40 with 15 minutes remaining, but the Bulldogs answered with a 20-2 run for a 71-42 advantage with about 11 minutes left.
The Bulldogs are looking for their third straight NCAA Tournament bid — something they haven’t done since 2005.
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